The Justice Department lost two senior officials Friday. Jason Reding Quiñones resigned as U.S. attorney for the Southern District of Florida, whose office has been involved in investigations of former U.S. officials. Attorney General Todd Blanche separately accepted the resignation of John Eisenberg, the assistant attorney general who led the National Security Division.

Quiñones said his resignation took effect Nov. 6. Blanche confirmed the departure in a separate announcement. In his statement on Eisenberg, Blanche said he had accepted the resignation and credited Eisenberg with overseeing terrorism prosecutions and work to disrupt planned attacks. The statements gave no reason for either departure and named no successors. Blanche gave no effective date for Eisenberg’s departure.

The South Florida investigations

Exterior of a federal courthouse in Miami
A federal courthouse in Miami in May 2007.Miami92, Wikimedia Commons, public domain.

The Southern District of Florida is a federal judicial district with courthouses in cities including Miami, Fort Lauderdale and Fort Pierce. Its U.S. attorney leads the office that represents the federal government there. The office has drawn national attention because of inquiries involving former CIA Director John Brennan and other former officials. Those inquiries concern events that predate Quiñones’s departure.

The clearest public account of the separate inquiries is an Oct. 15 opinion in Brennan v. Blanche. In describing Brennan’s lawsuit, the court recounted his allegations that the Justice Department was investigating whether former officials had conspired to violate President Donald Trump’s civil rights. The opinion refers to that investigation by the name used in the filings, the Grand Conspiracy case. The court separately described an investigation into whether Brennan gave false testimony to Congress in 2023.

The opinion said the two investigations had led to three grand jury inquiries. One South Florida inquiry concerned the alleged conspiracy. A second in South Florida and a third in Washington concerned the alleged false statements. The court said none had resulted in an indictment as of its Oct. 15 opinion. That is the status the court recorded on that date. The resignation announcements offered no update on those inquiries.

What the judge decided in October

Brennan sued to make the government preserve records he said he might need to defend himself if prosecutors ever brought charges. He argued that those records could help him show why the government decided to prosecute him. The district judge dismissed the lawsuit because Brennan lacked standing to seek that relief. The opinion concluded that the feared harm depended on several uncertain events, including an indictment and the loss of relevant records.

The ruling addressed a records-preservation lawsuit in Washington. It did not decide whether Brennan had committed a crime or whether prosecutors had sufficient evidence to charge him. The opinion also explained that a grand jury could decline to indict even if prosecutors sought charges.

A leadership change can affect who supervises prosecutors, but it does not by itself resolve an inquiry. Friday’s announcements did not say who would supervise the South Florida work or whether the department would change its scope. The October opinion describes the court proceedings through that point, while any later public filing would have to establish what changed afterward.

The national security post is separate

An exterior door at the Justice Department headquarters
An entrance to the Justice Department headquarters in March 2025.Sdkb, Wikimedia Commons, CC BY-SA 4.0.

Eisenberg was sworn in on June 5, 2025, according to his Justice Department biography. He led a division based in Washington with a nationwide remit. The National Security Division handles federal work involving terrorism, espionage and other national security threats. Its lawyers work with federal prosecutors and agencies, including on cases that arise outside Washington.

Blanche’s two statements described distinct jobs. The South Florida U.S. attorney runs a regional federal prosecution office. The assistant attorney general oversees the national security division at department headquarters. The department’s announcements left two separate succession questions open.